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Korean Journal of Neuromuscular Disorders 2015;7(2):56-63.
Cancer-related Neuropathies
Sun-Young Kim
Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
암과 관련된 신경병증
김선영
울산대학교 의과대학 울산대학교병원 신경과
Abstract
Peripheral neuropathies are the most common neurologic complications of cancer. The spectrum of peripheral nervous system dysfunction in cancer patients is broad; direct nerve compression or infiltration by tumor; neurotoxicity of cancer treatment; nutritional deficiencies; metabolic derangement; and paraneoplastic disorders. Among them, paraneoplastic neuropathies are important because, they may have unique phenotypic presentations, such as sensory neuronopathy, autonomic neuropathy, demyelinating neuropathy, and rarely motor neuron disease. Immunomodulatory therapy, such as corticosteroid, IV immunoglobulin, or immunosuppressants, may benefit some cancer patients with peripheral neuropathies.
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